Alpha-GPC came up with a genuine on-air endorsement 10 times across the episodes we processed. This page collects every one of those moments: who said it, what they said, and the exact point in the episode.
Few supplements cross as many shows as Alpha-GPC does. It has come up on Andrew Huberman, Joe Rogan, Lex Fridman, and Tim Ferriss, ten times in total, usually in conversations about focus and cognitive performance.
That kind of spread across four very different hosts is rare, and it is why we built this page. Every mention is quoted and timestamped so you can hear the actual context, not just a headline number.
“I will take 500 mg of PEA and I'll take 300 mg of alpha-GPC. It leads to a sharp but very transient increase in dopamine” — Andrew Huberman 00:31:10
Huberman explains how dopamine drives motivation and how to protect your baseline so effort itself becomes rewarding.
“600 milligrams of alpha GPC is going to make you more alert; that's one that I would put kind of high on the tier things for if you want alertness and focus” — Andrew Huberman 01:11:14
Andrew Huberman and Joe Rogan riff on olfaction, doing hard things, elite athletes' nervous systems, media distortion, and authenticity.
“Alpha GPC taken in 300 milligram form 10 to 30 minutes before a about of cognitive work or a about of physical work will increase your focus” — Andrew Huberman 00:07:16
Huberman separates nicotine's real cognitive benefits from the deadly delivery devices, and details the science of quitting smoking and vaping.
“The most effective one I've found is Alpha-GPC. Alpha-GPC consumed at dosages of 300 milligrams to 600 milligrams prior to a work about... greatly increase one's ability to focus” — Andrew Huberman 01:30:05
Andrew Huberman delivers a toolkit of mostly zero-cost behavioral, nutritional, and supplement protocols to measurably improve focus and concentration.
“I take 300 milligrams of Alpha-GPC now and again, before some cognitive work, sometimes before workouts, and I do subjectively feel that it narrows my focus” — Andrew Huberman 01:00:16
Peter Attia gives Andrew Huberman a clinic-grade masterclass on the blood markers, exercise, and hormones that actually extend lifespan and health span.
“Supplements that I have used and do use for increasing acetylcholine are things like Alpha GPC or Huperzinene.” — Andrew Huberman 01:41:21
Huberman explains how four neuromodulators run your brain, and the food, light, cold, and supplements that let you tune them.
“300 Mig to 600 migs of alpha GPC with a cup of espresso if you're well rested you're like a laser for 90 minutes” — Andrew Huberman 02:22:54
Huberman and Fridman roam from food, friendship and Rick Rubin to focus, stress, sauna science, sex, and how to ready your brain for hard work.
“Things like alpha GPC, which I personally use, things like phosphatidylserine, which I also use on occasion.” — Andrew Huberman 00:08:59
Andrew Huberman breaks down the neuroscience of desire, love, and attachment, framing all three as products of autonomic nervous system coordination.
“I will take 500 milligrams of PEA and I'll take 300 milligrams of Alpha-GPC. That's something that I personally do.” — Andrew Huberman 02:07:39
Andrew Huberman explains how dopamine baselines and peaks really work, and how to harness them for lasting motivation, focus, and satisfaction.
“i think alpha gpc has real effects that are supported by quality peer-reviewed studies ... i use it from time to time” — Andrew Huberman 02:13:03
Stanford neurobiologist Andrew Huberman on using light, breathing, and the body to control sleep, stress, and performance.
