How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Creatine monohydrate

“I certainly feel better when I'm taking five grams of creatine monohydrate per day. I know most people take it for muscle growth”— Andrew Huberman

Magnesium threonate

“okay to take every night or nearly every night are things like magnesium 3 and 8, apigenin, if that's not true, correct me. I certainly take them every night”— Andrew Huberman

Apigenin

“things like magnesium 3 and 8, apigenin, if that's not true, correct me. I certainly take them every night”— Andrew Huberman

Tongkat ali (longjack)

“the dosage that I've been using for years now is, it's 400 milligrams taken once a day, typically early in the day”— Andrew Huberman

Brazil nuts

“I definitely make sure I get enough selenium by eating three to five Brazil nuts per day. Which I very much enjoy the taste of also.”— Andrew Huberman

Garlic (allicin) capsule

“one can take 600 milligrams of garlic capsule for the allicin... And that had a remarkable effect in reducing TMAO.”— Andrew Huberman

Ambien

Sanofi (inferred)

“An example of a benzo would be Xanax. An example of a non benzo would be Ambien. So those all work on GABA.”— guest

Xanax

Pfizer (inferred)

“So an example of a benzo would be Xanax. An example of a non benzo would be Ambien.”— guest

BioPerine (black pepper extract)

Sabinsa (inferred)

“Black pepper extract. So it's used often to increase bioavailability. It's also called BioPerine. It's also a 5-alpha-reductase inhibitor.”— guest

Saw palmetto

“a supplement known as saw palmetto, which a lot of older men take for their prostate health or finasteride”— guest

Finasteride

“or finasteride, which you can take for your prostate, or your heart, or your hair, or dutasteride.”— guest

Dutasteride

“or finasteride, which you can take for your prostate, or your heart, or your hair, or dutasteride.”— guest

Minoxidil

“And minoxidil does this too, but you're really just having a new, healthier follicle.”— guest

Metformin

“does everybody need to be on metformin that has PCOS? Not necessarily, but metformin is one of the tools that can help with insulin sensitization.”— guest

Myo-inositol

“Other tools that can help are inositol, so myo-inositol is an insulin sensitizer.”— guest

D-chiro-inositol

“Its cousin D-chiro-inositol is a weak antiandrogen. A lot of types of inositol have both of those in it.”— guest

Spironolactone

“talked to your doctor about getting on the oral contraceptive or spironolactone, which is also an anti-androgen, but it happens to be a potassium-sparing diuretic”— guest

DIM (diindolylmethane)

“DIM or diindolylmethane is another kind of weak antiestrogen, antiandrogen that a lot of women should consider as well.”— guest

Slynd

Exeltis (inferred)

“there's one known as Slynd, which is made from spironolactone. So some women are on spironolactone”— guest

Trazodone

“if you're taking a sleep supplement, it should not be taken every night. Another one of them is Trazodone.”— guest

GABA (supplement)

“I occasionally take 100 to 200 milligrams of GABA in order to enhance sleep. But I do it maybe every third or four nights.”— Andrew Huberman

L-theanine

“Magnesium's one of the exceptions. L-theanine is also another exception.”— guest

Calcium D-glucarate

“calcium D-glucarate is a supplement that can help with estrogen control.”— guest

Tadalafil (Cialis)

Eli Lilly (inferred)

“A lot of men take to tadalafil, generic is Cialis, has a much longer half-life than Viagra or Levitra. Its half-life is almost a day.”— guest

Flomax (tamsulosin)

Boehringer Ingelheim (inferred)

“We used to use other medications like Flomax, which is tamsulosin. That's an alpha antagonist”— guest

Viagra (sildenafil)

Pfizer (inferred)

“Some interesting studies on Viagra have been done as well. It can potentially alter your rays and cones in your eye.”— guest

Levitra

Bayer (inferred)

“generic is Cialis, has a much longer half-life than Viagra or Levitra.”— guest

L-carnitine

“you can alter the sensitivity of your androgen receptor with things like L-carnitine and tadalafil as mentioned.”— guest

Turkesterone

“People know about Turkesterone and also Beta-Ecdysterone, which are two ecdysteroids that are beta estradiol receptor agonist.”— guest

Beta-Ecdysterone (ecdysterone)

“People know about Turkesterone and also Beta-Ecdysterone, which are two ecdysteroids that are beta estradiol receptor agonist.”— guest

Fadogia agrestis

“Fadogia agrestis has just reached a point where we have enough evidence till we know it probably helps both with luteinizing hormone release”— guest

Boron

“so boron can help regulate SHBG, but its effect is mostly acute. So it's unlikely to have a bad effect”— guest

JATENZO (testosterone undecanoate)

Clarus Therapeutics (inferred)

“it is FDA approved. So it is brand name now. it's called JATENZO.”— guest

hCG (human chorionic gonadotropin)

“Yeah, some people are on hCG monotherapy. It can be slightly better on your lipids than being on TRT.”— guest

Selenium

“So if you take hCG, then it can potentially improve your thyroid function. So that along with selenium are likely the two best things that you can do for thyroid health.”— guest

Vitamin B6 (P5P, pyridoxine-5-pyrophosphate)

“They can take dopamine agonist that agonize that D2 receptor like P5P, which is essentially vitamin B6.”— guest

Vitamin E (mixed tocopherols)

“Vitamin E can also help, especially if it's mixed to tocopherols.”— guest

Cabergoline

“I'm aware of a number of people who take dopamine agonists, L-tyrosine, cabergoline, things like that, to really boost their dopamine levels.”— Andrew Huberman

L-tyrosine

“I'm aware of a number of people who take dopamine agonists, L-tyrosine, cabergoline, things like that, to really boost their dopamine levels.”— Andrew Huberman

Adderall

“I know a number of people that do this through prescription drugs, Adderall, Ritalin, modafinil, and those drugs of course hit many transmitter systems”— Andrew Huberman

Ritalin

“I know a number of people that do this through prescription drugs, Adderall, Ritalin, modafinil, and those drugs of course hit many transmitter systems”— Andrew Huberman

Modafinil

“I know a number of people that do this through prescription drugs, Adderall, Ritalin, modafinil, and those drugs of course hit many transmitter systems”— Andrew Huberman

Wellbutrin

“People taking antidepressants like Wellbutrin tap into that system.”— Andrew Huberman

Alpha-GPC

“So any choline precursor like Alpha-GPC or phosphatidylserine, it'll will convert them more or less to TMAO.”— guest

Sermorelin

“For instance sermorelin, tesamorelin, ipamorelin, to stimulate the release of growth hormone rather than taking growth hormone.”— Andrew Huberman

Tesamorelin (Egrifta/Evista)

Theratechnologies (inferred)

“tesamorelin was recently FDA approved for something called lipodystrophy. It happens where body fat is displaced into abnormal areas”— guest

Ipamorelin

“For instance sermorelin, tesamorelin, ipamorelin, to stimulate the release of growth hormone rather than taking growth hormone.”— Andrew Huberman

BPC-157

“BPC-157, which is essentially a synthetic gastric juice that normally repairs the gut, being used to treat injuries.”— Andrew Huberman

GHK-copper peptide

“There are peptides like GHK-copper peptide which is produced endogenously in the liver more at younger ages.”— guest

TB-500 (thymosin beta-4)

“TB-500 or a thymosin beta-4 analog. And then we can also talk about bremelanotide, which is melanotan III.”— guest

Bremelanotide (PT-141)

“it's also known as PT-141, it helps significantly. A lot of times you use it in nasal spray. It goes straight into the central nervous system”— guest

Avastin

Genentech (inferred)

“So another medication known as Avastin. It's on the WHO's list of essential medications for cancer.”— guest

Insulin

“My favorite peptide is the original peptide, which is insulin. So insulin is a peptide”— guest

ReliOn insulin (NPH)

ReliOn (inferred)

“there is over-the-counter insulin, ReliOn or NPH, but ideally your insulin is prescribed by your doctor”— guest

Naltrexone

“naltrexone can actually potentially help antagonize that to increase LH as well, especially in people recovering from opiates”— guest

Gabapentin

“alcohol works on GABA as well. Gabapentin also works on GABA. Migraine medicines, many of them work on GABA.”— guest