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Joe Rogan · 2025-09-09

Joe Rogan Experience #2376 - Brigham Buhler

A Ways2Well founder and ex-pharma rep walks Joe Rogan through alleged FDA capture, the war on peptides, and where biotech and AI take humanity next.

Joe Rogan Experience #2376 - Brigham Buhler
The guest

Brigham Buhler: Founder of Ways2Well and the compounding pharmacy Revive Rx, and a former Eli Lilly drug rep turned medical-device rep and lab owner. He is a Make America Healthy Again (MAHA) advocate who has testified before the U.S. Senate and the Texas legislature on health policy.

What this episode covers

Buhler details what he says is deep corporate capture across the FDA, CDC, NIH and EPA, focusing on a 'war on peptides' in which big pharma (Eli Lilly, Novo Nordisk) lobbies to ban compounded GLP-1s and reclassify drugs as biologics to extend patents and kill price competition. He recounts FDA meetings, leaks from 'moles,' and emergency calls with HHS Secretary RFK Jr. The conversation expands into SSRIs versus placebo, ultra-processed food and glyphosate fights in Texas, psychedelics for addiction, and regenerative medicine (peptides, stem cells, red light, hyperbaric). The final hour turns philosophical: AI, CRISPR gene editing, transhumanism, UAPs, the tridactyl Peru mummies, and whether humanity must merge with technology to survive.

The guest's own work

ProductBy the guest

Ways2Well

Brigham Buhler

“I take Waste to Well vitamins. I take eight of them. I just throw them in my mouth, swallow them all at once.”— Joe Rogan
ProductBy the guest

Revive Rx (Revive compounding pharmacy)

Brigham Buhler

“We sit we ship 6,000 bottles of medication a day at my pharmacy revive. We have had minimal side effects in literally over a decade.”— guest

Also referenced (named, not recommended)

ProductReferenced

Meta Quest

Meta

“MetaQuest, dude. Pretty incredible. Pretty fun. Pretty exciting, you know.”— Joe Rogan
BookReferencedISBN verified

Hacking Darwin

Jamie Metzl

“Hacking Darwin, the book Hacking Darwin explains all this and the direction we're headed and how you would be able to essentially”— guest
BookReferencedISBN verified

The Art of the Deal

Donald Trump

“President Trump, the art of the deal, the master negotiator is attempting to play hard ball with big pharma.”— guest
BookReferencedISBN verified

The Book of Enoch

Anonymous

“the book of Enoch which I know isn't like technically... I'm reading that right now. I've got it on audiobook right now. Listening to it every day.”— Joe Rogan

Big reveals from this episode

  • Says an FDA insider called him after a 'friendly' meeting and warned: 'they're going to smile, [expletive] you.'
  • Claims 100% of recent blockbuster drugs had their roots at the NIH, then were monopolized by big pharma.
  • Says he has texted RFK Jr. twice and got a call back within 10 minutes both times, prompting an emergency FDA mandate on peptides.
  • Claims the CDC's Atlanta headquarters was gifted by Coca-Cola and that the CDC worked to suppress sugar science.
  • As a former Lilly rep, says the serotonin-imbalance theory of depression is 'hogwash' and SSRIs beat placebo by only ~2 points on a 52-point scale.
  • Reveals Jelly Roll lost 200 lbs through his program and insisted on doing it without a GLP-1.
  • Recounts winning three MAHA bills in Texas 31-0 in the Senate against lobbyists from the American Heart Association, Coca-Cola and Pepsi.
  • Frames AI as a global race in which competing labs are 'in competition to see who creates God.'

Worth remembering

  • Buhler argues GLP-1 dosing is set by insurance reimbursement rates rather than what is medically best for the patient.
  • A standard drug patent runs ~5 years, but a biologic patent runs 12 years, the alleged motive for reclassifying drugs.
  • Says the CDC was founded in WWII to fight malaria and partnered with Monsanto to spread DDT.
  • Claims exercise outperforms antidepressants by ~5x and red light therapy by ~2x versus placebo in studies.
  • Cites psychedelic-assisted addiction success rates of ~83% after one experience and ~94% after two.
  • Claims 100% of Monsanto's chemicals come from China and that 94% of Americans show glyphosate in their blood.
  • Says ~70% of glyphosate exposure comes from spraying crops to dry them for faster harvest in the final week.
  • Brain weight is now roughly a plastic-fork's worth of microplastics, per the figures discussed.
  • Claims CRISPR could edit in ~20 IQ points, framed as 'the difference between Arnold Schwarzenegger and Albert Einstein.'
  • Discusses newly developed contact lenses that give infrared vision even with eyes closed.